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St. Joseph Regional Cancer Center
List of Active Protocols
May 20, 2008
BREAST
1) ECOG-PACCT-1 - Program for the Assessment of clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial2) NSABP B-36 - A Clinical Trial of Adjuvant Therapy Comparing six cycles of 5-FU, Epirubicin and Cyclophosphamide(FEC) to Four Cycles of Adriamycin and Cyclophosphamide in Patients with Node Negative Breast Cancer
3) NSABP- B-42 -A Clinical Trial to Determine the Efficacy of Five Years of Letrozole compared to Placebo in patients completing five years of Hormonal Therapy consisting of an Aromatase Inhibitor (AI) or Tamoxifen Followed by an AI in Prolonging Disease Free Survival in Postmenopausal Women with Hormone Receptor Positive Breast Cancer
HODGKINS/NON-HODGKINS LYMPHOMA
None
LUNG (NON-SMALL CELL) / SMALL CELL
None
GYNECOLOGIC
None
GASTROINTESTINAL
1) E5204- Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil and Leucovorin vx. Oxaliplatin, 5-Fluorouracil, Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-operative Chemoradiation2) CALGB/SWOG C80405-A phase III trial of Irinotecan/5FU/Leucovorin or Oxaliplatin/5FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum
3) GIST Registry-CSTI5721BUS227- Gastrointestinal Stromal Tumor
4) AVF3991n- An Observational Study of Avastin (Bevacizumab) in combination with Chemotherapy for Treatment of Metastatic or Locally Advanced and Unresectable Colorectal Cancer, Locally Advanced or Metastatic Non-Small Cell Lung (Excluding predominant Squamous Cell Histology) or Locally Recurrent or Metastatic Breast Cancer
5) NSABP-R-04- A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with or without Oxaliplatin with Preoperative Radiation Therapy and Continuous Intravenous Infusion of 5-FU with or without Oxaliplatin in the Treatment of Patients with Operable Carcinoma of the Rectum
6) N0147- A Randomized Phase III Trial of Oxaliplatin (OXAL) Plus 5-Fluorouracil (5-FU)/Leucovorin (CF) with or without Cetuximab (C225) after Curative Resection for Patients with Stage III Colon Cancer
GENITOURINARY
1) RTOG-0415- A Phase III Randomized Study of Hypofractionated 3D-CRT/IMRT in Patients with Favorable-Risk Prostate Cancer2) RTOG-0521- A Phase III Protocol of Androgen Suppression (AS) and 3DRT/IMRT vs. AS and 3DCRT/IMRT Followed by Chemotherapy with Docetaxel and Prednisone for Localized High-Risk Prostate Cancer
HEAD/NECK
None
BRAIN
1) N0574- A Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in patients with one to three cerebral Metastases
OTHER
WORLD CML Registry, CSTI 571A2402-A Worldwide, Observational Registry collecting Longitudinal Data on the management of Chronic Myelogenous Leukemia (CML) patients (The WORLD CML Registry) in routine practice
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